Inflammatory bowel disease, alpha-Synuclein aggregates and Parkinson’s disease

Project: Research

Project Details

Description

-To assess the presence and characteristics of alpha-Synuclein (AS) aggregates in gut biopsies of inflammatory bowel disease (IBD) patients.
- To search for motor/non-motor symptoms of PD in patients with IBD and controls;

-To correlate the AS burden in gut biopsies with the IBD type: Crohn’s or colitis;

- To correlate the AS burden in IBD patients with its clinical-morphological features, disease duration/activity and treatment;

-To promote specialized neurological evaluation in patients with IBD or controls with PD suggestive symptoms or exhibiting significant AS burden in gut biopsies.
AcronymInflamaSPark
StatusFinished
Effective start/end date31/01/2231/01/24

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