TY - JOUR
T1 - Adsorptive micro-extraction techniques-Novel analytical tools for trace levels of polar solutes in aqueous media
AU - Neng, N. R.
AU - Silva, A. R.M.
AU - Nogueira, J. M.F.
N1 - Funding Information:
Nuno R. Neng ( BD 38660/2007 ) and Ana Rita M. Silva ( BD 40926/2007 ) acknowledge Fundação para a Ciência e a Tecnologia for the PhD grants.
PY - 2010/11/19
Y1 - 2010/11/19
N2 - A novel enrichment technique, adsorptive μ-extraction (AμE), is proposed for trace analysis of polar solutes in aqueous media. The preparation, stability tests and development of the analytical devices using two geometrical configurations, i.e. bar adsorptive μ-extraction (BAμE) and multi-spheres adsorptive μ-extraction (MSAμE) is fully discussed. From the several sorbent materials tested, activated carbons and polystyrene divinylbenzene phases demonstrated the best stability, robustness and to be the most suitable for analytical purposes. The application of both BAμE and MSAμE devices proved remarkable performance for the determination of trace levels of polar solutes and metabolites (e.g. pesticides, disinfection by-products, drugs of abuse and pharmaceuticals) in water matrices and biological fluids. By comparing AμE techniques with stir bar sorptive extraction based on polydimethylsiloxane phase, great effectiveness is attained overcoming the limitations of the latter enrichment approach regarding the more polar solutes. Furthermore, convenient sensitivity and selectivity is reached through AμE techniques, since the great advantage of this new analytical technology is the possibility to choose the most suitable sorbent to each particular type of application. The enrichment techniques proposed are cost-effective, easy to prepare and work-up, demonstrating robustness and to be a remarkable analytical tool for trace analysis of priority solutes in areas of recognized importance such as environment, forensic and other related life sciences.
AB - A novel enrichment technique, adsorptive μ-extraction (AμE), is proposed for trace analysis of polar solutes in aqueous media. The preparation, stability tests and development of the analytical devices using two geometrical configurations, i.e. bar adsorptive μ-extraction (BAμE) and multi-spheres adsorptive μ-extraction (MSAμE) is fully discussed. From the several sorbent materials tested, activated carbons and polystyrene divinylbenzene phases demonstrated the best stability, robustness and to be the most suitable for analytical purposes. The application of both BAμE and MSAμE devices proved remarkable performance for the determination of trace levels of polar solutes and metabolites (e.g. pesticides, disinfection by-products, drugs of abuse and pharmaceuticals) in water matrices and biological fluids. By comparing AμE techniques with stir bar sorptive extraction based on polydimethylsiloxane phase, great effectiveness is attained overcoming the limitations of the latter enrichment approach regarding the more polar solutes. Furthermore, convenient sensitivity and selectivity is reached through AμE techniques, since the great advantage of this new analytical technology is the possibility to choose the most suitable sorbent to each particular type of application. The enrichment techniques proposed are cost-effective, easy to prepare and work-up, demonstrating robustness and to be a remarkable analytical tool for trace analysis of priority solutes in areas of recognized importance such as environment, forensic and other related life sciences.
KW - Adsorptive micro-extraction (AμE)
KW - Analytical separation techniques
KW - Bar adsorptive micro-extraction (BAμE)
KW - Multi-spheres adsorptive micro-extraction (MSAμE)
KW - Polar compounds
KW - Sample enrichment techniques
KW - Trace analysis
UR - http://www.scopus.com/inward/record.url?scp=78049232317&partnerID=8YFLogxK
U2 - 10.1016/j.chroma.2010.09.048
DO - 10.1016/j.chroma.2010.09.048
M3 - Article
C2 - 20950811
AN - SCOPUS:78049232317
SN - 0021-9673
VL - 1217
SP - 7303
EP - 7310
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - 47
ER -