Cardiometabolic risk, inflammation, and neurodegenerative disorder

Filipe Palavra; Ethel Ciampi Díaz; Armando Sena

doi:10.1007/978-3-319-16018-4_7

Cardiometabolic risk, inflammation, and neurodegenerative disorder

Filipe Palavra, Ethel Ciampi Díaz, Armando Sena

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

Inflammation has been recognized as an important character in the underlying mechanisms leading to the development of various types of neurodegenerative disorders. In this sense, both inflammation of the nervous system itself and systemic inflammation act in the complex pathophysiology of these neurological diseases. The nervous system does not play a passive role in the complexity of these mechanisms and can itself be responsible for perpetuating pro-inflammatory stimuli – it is today recognized the important role that specific brain areas play in the so-called metabolic inflammation. This dialectical relationship will be the focus of this chapter.

Original language	English
Title of host publication	Biomarkers of Cardiometabolic Risk, Inflammation and Disease
Publisher	Springer International Publishing
Pages	133-159
Number of pages	27
ISBN (Electronic)	9783319160184
ISBN (Print)	9783319160177
DOIs	https://doi.org/10.1007/978-3-319-16018-4_7
Publication status	Published - 1 Jan 2015

Keywords

Alzheimer’s disease
Inflammation
Inflammation mediators
Metabolic syndrome
Multiple sclerosis
Neurodegenerative diseases

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10.1007/978-3-319-16018-4_7

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AU - Palavra, Filipe

AU - Díaz, Ethel Ciampi

AU - Sena, Armando

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AB - Inflammation has been recognized as an important character in the underlying mechanisms leading to the development of various types of neurodegenerative disorders. In this sense, both inflammation of the nervous system itself and systemic inflammation act in the complex pathophysiology of these neurological diseases. The nervous system does not play a passive role in the complexity of these mechanisms and can itself be responsible for perpetuating pro-inflammatory stimuli – it is today recognized the important role that specific brain areas play in the so-called metabolic inflammation. This dialectical relationship will be the focus of this chapter.

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KW - Inflammation mediators

KW - Metabolic syndrome

KW - Multiple sclerosis

KW - Neurodegenerative diseases

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ER -

Cardiometabolic risk, inflammation, and neurodegenerative disorder

Abstract

Keywords

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