Characterization of multidrug-resistant diabetic foot ulcer enterococci

Teresa Semedo-Lemsaddek, Carla Mottola, Cynthia Alves-Barroco, Patrícia Cavaco-Silva, Luís Tavares, Manuela Oliveira

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Introduction Diabetes mellitus is a highly prevalent chronic progressive disease with complications that include diabetic-foot ulcers. Methods Enterococci isolated from diabetic-foot infections were identified, evaluated by macro-restriction analysis, and screened for virulence traits and antimicrobial resistance. Results All isolates were considered multidrug-resistant, cytolysin and gelatinase producers, and the majority also demonstrated the ability to produce biofilms. Conclusions These results indicate the importance of enterococci in diabetic-foot infection development and persistence, especially regarding their biofilm-forming ability and resistance to clinically relevant antibiotics.

Original languageEnglish
Pages (from-to)114-116
Number of pages3
JournalEnfermedades Infecciosas y Microbiologia Clinica
Volume34
Issue number2
DOIs
Publication statusPublished - 1 Feb 2016

Keywords

  • Biofilms
  • Diabetic foot infections
  • Enterococcus
  • Multi-drug-resistant (MDR)
  • Virulence factors

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