TY - JOUR
T1 - Characterization of multidrug-resistant diabetic foot ulcer enterococci
AU - Semedo-Lemsaddek, Teresa
AU - Mottola, Carla
AU - Alves-Barroco, Cynthia
AU - Cavaco-Silva, Patrícia
AU - Tavares, Luís
AU - Oliveira, Manuela
N1 - Publisher Copyright:
© 2015 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Introduction Diabetes mellitus is a highly prevalent chronic progressive disease with complications that include diabetic-foot ulcers. Methods Enterococci isolated from diabetic-foot infections were identified, evaluated by macro-restriction analysis, and screened for virulence traits and antimicrobial resistance. Results All isolates were considered multidrug-resistant, cytolysin and gelatinase producers, and the majority also demonstrated the ability to produce biofilms. Conclusions These results indicate the importance of enterococci in diabetic-foot infection development and persistence, especially regarding their biofilm-forming ability and resistance to clinically relevant antibiotics.
AB - Introduction Diabetes mellitus is a highly prevalent chronic progressive disease with complications that include diabetic-foot ulcers. Methods Enterococci isolated from diabetic-foot infections were identified, evaluated by macro-restriction analysis, and screened for virulence traits and antimicrobial resistance. Results All isolates were considered multidrug-resistant, cytolysin and gelatinase producers, and the majority also demonstrated the ability to produce biofilms. Conclusions These results indicate the importance of enterococci in diabetic-foot infection development and persistence, especially regarding their biofilm-forming ability and resistance to clinically relevant antibiotics.
KW - Biofilms
KW - Diabetic foot infections
KW - Enterococcus
KW - Multi-drug-resistant (MDR)
KW - Virulence factors
UR - http://www.scopus.com/inward/record.url?scp=84958750850&partnerID=8YFLogxK
U2 - 10.1016/j.eimc.2015.01.007
DO - 10.1016/j.eimc.2015.01.007
M3 - Article
C2 - 25704893
AN - SCOPUS:84958750850
SN - 0213-005X
VL - 34
SP - 114
EP - 116
JO - Enfermedades Infecciosas y Microbiologia Clinica
JF - Enfermedades Infecciosas y Microbiologia Clinica
IS - 2
ER -