Dysbiosis, small intestinal bacterial overgrowth, and chronic diseases: A translational approach

Ana Rita Silva, Maria Alexandra Bernardo, Maria Fernanda Mesquita, José Vaz Patto, Pedro Moreira, Patrícia Padrão, Maria Leonor Silva

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

Dysbiosis is characterized by an alteration in quantity and quality of intestinal microbiota composition. In the presence of dysbiosis, enterocytes will have difficulty in maintaining the integrity of the mucosal barrier, leading to increased intestinal permeability. These events are recognised to be linked to several chronic diseases. One of the consequences of dysbiosis is the manifestation of small intestinal bacterial overgrowth (SIBO), which is associated to a variety of chronic diseases. Single food nutrients and bioactive molecules, food additives, pre- and probiotics, and different dietary patterns may change the composition of the intestinal microbiota. Low FODMAPs diet has been a reference in SIBO treatment. This chapter intends to describe how the intestinal microbiota, dysbiosis, and SIBO can be related; to define dysbiosis food and nutrients influence; and to offer some nutritional therapy strategies for applying the low FODMAPs protocol, enabling better adherence by patients in order to increase their wellbeing.

Original languageEnglish
Title of host publicationTreating Endocrine and Metabolic Disorders With Herbal Medicines
PublisherIGI Global
Pages334-362
Number of pages29
ISBN (Electronic)9781799848097
ISBN (Print)9781799848080
DOIs
Publication statusPublished - 11 Dec 2020

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