TY - JOUR
T1 - Electrochemical Enzyme Biosensors Revisited
T2 - Old Solutions for New Problems
AU - Monteiro, Tiago
AU - Almeida, Maria Gabriela
N1 - Publisher Copyright:
© 2018, © 2018 Taylor & Francis Group, LLC.
PY - 2019/1/2
Y1 - 2019/1/2
N2 - Worldwide legislation is driving the development of novel and highly efficient analytical tools for assessing the composition of every material that interacts with Consumers or Nature. The biosensor technology is one of the most active R&D domains of Analytical Sciences focused on the challenge of taking analytical chemistry to the field. Electrochemical biosensors based on redox enzymes, in particular, are highly appealing due to their usual quick response, high selectivity and sensitivity, low cost and portable dimensions. This review paper aims to provide an overview of the most important advances made in the field since the proposal of the first biosensor, the well-known hand-held glucose meter. The first section addresses the current needs and challenges for novel analytical tools, followed by a brief description of the different components and configurations of biosensing devices, and the fundamentals of enzyme kinetics and amperometry. The following sections emphasize on enzyme-based amperometric biosensors and the different stages of their development.
AB - Worldwide legislation is driving the development of novel and highly efficient analytical tools for assessing the composition of every material that interacts with Consumers or Nature. The biosensor technology is one of the most active R&D domains of Analytical Sciences focused on the challenge of taking analytical chemistry to the field. Electrochemical biosensors based on redox enzymes, in particular, are highly appealing due to their usual quick response, high selectivity and sensitivity, low cost and portable dimensions. This review paper aims to provide an overview of the most important advances made in the field since the proposal of the first biosensor, the well-known hand-held glucose meter. The first section addresses the current needs and challenges for novel analytical tools, followed by a brief description of the different components and configurations of biosensing devices, and the fundamentals of enzyme kinetics and amperometry. The following sections emphasize on enzyme-based amperometric biosensors and the different stages of their development.
KW - Amperometry
KW - analysis and diagnostics
KW - biosensors
KW - electron transfer principles
KW - redox enzymes
UR - http://www.scopus.com/inward/record.url?scp=85046905098&partnerID=8YFLogxK
U2 - 10.1080/10408347.2018.1461552
DO - 10.1080/10408347.2018.1461552
M3 - Review article
C2 - 29757683
AN - SCOPUS:85046905098
SN - 1040-8347
VL - 49
SP - 44
EP - 66
JO - Critical Reviews in Analytical Chemistry
JF - Critical Reviews in Analytical Chemistry
IS - 1
ER -