In vitro reassembly of the malolactic fermentation pathway of Leuconostoc oenos (Oenococcus oeni)

Madalena Salema, Inácia Capucho, Bert Poolman, M. V. San Romão, Maria C. Loureiro Dias

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

The mechanism of metabolic energy generation by malolactic fermentation was studied with artificial membrane vesicles of Leuconostoc oenos (Oenococcus oeni). (Note that although L. oenos was recently reclassified as O. oeni [L. M. T. Dicks, F. Dellaglio, and M.D. Collins, Int. J. Syst. Bacteriol. 45:395-397, 1995], the old designation was kept in the present work.) Purified malolactic enzyme was entrapped in artificial membrane vesicles prepared from L. oenos cells able to transport L-malate. We show that the in vitro reconstituted system, including an electrogenic L-malate carrier and the decarboxylating malolactic enzyme, generated a proton motive force that was able to drive intravesicular accumulation of leucine.

Original languageEnglish
Pages (from-to)5537-5539
Number of pages3
JournalJournal of Bacteriology
Volume178
Issue number18
DOIs
Publication statusPublished - 1996
Externally publishedYes

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