Intrahepatic clear cell cholangiocarcinoma - An uncommon histologic subtype: Case report and literature review

Samuel Raimundo Fernandes; Cilénia Baldaia; Hugo Pinto Marques; Francisco Tortosa; Fernando Ramalho

doi:10.17235/reed.2017.4239/2016

Intrahepatic clear cell cholangiocarcinoma - An uncommon histologic subtype: Case report and literature review

Samuel Raimundo Fernandes, Cilénia Baldaia, Hugo Pinto Marques, Francisco Tortosa, Fernando Ramalho

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.

Original language	English
Pages (from-to)	382-384
Number of pages	3
Journal	Revista Espanola de Enfermedades Digestivas
Volume	109
Issue number	5
DOIs	https://doi.org/10.17235/reed.2017.4239/2016
Publication status	Published - 2017
Externally published	Yes

Keywords

Clear-cell carcinoma
Intrahepatic cholangiocarcinoma
Liver nodule

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.17235/reed.2017.4239/2016

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title = "Intrahepatic clear cell cholangiocarcinoma - An uncommon histologic subtype: Case report and literature review",

abstract = "Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.",

keywords = "Clear-cell carcinoma, Intrahepatic cholangiocarcinoma, Liver nodule",

author = "Fernandes, {Samuel Raimundo} and Cil{\'e}nia Baldaia and Marques, {Hugo Pinto} and Francisco Tortosa and Fernando Ramalho",

note = "Publisher Copyright: {\textcopyright} 2017. SEPD y and AR{\'A}N EDICIONES, S.L.",

year = "2017",

doi = "10.17235/reed.2017.4239/2016",

language = "English",

volume = "109",

pages = "382--384",

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TY - JOUR

T1 - Intrahepatic clear cell cholangiocarcinoma - An uncommon histologic subtype

T2 - Case report and literature review

AU - Fernandes, Samuel Raimundo

AU - Baldaia, Cilénia

AU - Marques, Hugo Pinto

AU - Tortosa, Francisco

AU - Ramalho, Fernando

PY - 2017

Y1 - 2017

N2 - Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.

AB - Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.

KW - Clear-cell carcinoma

KW - Intrahepatic cholangiocarcinoma

KW - Liver nodule

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U2 - 10.17235/reed.2017.4239/2016

DO - 10.17235/reed.2017.4239/2016

M3 - Review article

C2 - 28155327

AN - SCOPUS:85025691161

SN - 1130-0108

VL - 109

SP - 382

EP - 384

JO - Revista Espanola de Enfermedades Digestivas

JF - Revista Espanola de Enfermedades Digestivas

IS - 5

ER -

Intrahepatic clear cell cholangiocarcinoma - An uncommon histologic subtype: Case report and literature review

Abstract

Keywords

UN SDGs

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