Lab-on-chip cytometry based on magnetoresistive sensors for bacteria detection in milk

Ana C. Fernandes, Carla M. Duarte, Filipe A. Cardoso, Ricardo Bexiga, Susana Cardoso, Paulo P. Freitas

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)

Abstract

Flow cytometers have been optimized for use in portable platforms, where cell separation, identification and counting can be achieved in a compact and modular format. This feature can be combined with magnetic detection, where magnetoresistive sensors can be integrated within microfluidic channels to detect magnetically labelled cells. This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer. In particular, we present an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk.

Original languageEnglish
Pages (from-to)15496-15524
Number of pages29
JournalSensors
Volume14
Issue number8
DOIs
Publication statusPublished - 21 Aug 2014
Externally publishedYes

Keywords

  • Cytometer
  • Magnetoresistive sensor
  • Microfluidic
  • Milk
  • Streptococcus agalactiae

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