Abstract
Seronegative HIV-1 infection has important implications for diagnosis and prevention. We describe a case of HIV-1 infection without seroconversion and fast progression to AIDS and death. Genetic and phylogenetic analysis indicated that the patient was infected with a CRF14-BG-like strain selectively transmitted by his seropositive sexual partner. The results suggest a massive infection with a highly aggressive CRF14-BG-like strain and/or the presence of an unidentified immunological deficiency that has prevented the formation of HIV-1-specific antibodies.
Original language | English |
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Pages (from-to) | 2359-2362 |
Number of pages | 4 |
Journal | AIDS |
Volume | 23 |
Issue number | 17 |
DOIs | |
Publication status | Published - Nov 2009 |