Recent progress in the field of glycoconjugates

Carina I.C. Crucho; Paula Correia-Da-Silva; Krasimira T. Petrova; M. Teresa Barros

doi:10.1016/j.carres.2014.10.005

Recent progress in the field of glycoconjugates

Carina I.C. Crucho
, Paula Correia-Da-Silva
, Krasimira T. Petrova
, M. Teresa Barros

Research output: Contribution to journal › Review article › peer-review

31 Citations (Scopus)

Abstract

The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and have provided new potential vaccines against cancer, viral, and bacterial infections and new biotechnological tools. This review aims to collect and compile the recent advances in the field of glycopeptides, glycoproteins, and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research, we hope that this review will inspire fruitful research in this important medicinal chemistry field.

Original language	English
Pages (from-to)	124-132
Number of pages	9
Journal	Carbohydrate Research
Volume	402
DOIs	https://doi.org/10.1016/j.carres.2014.10.005
Publication status	Published - 30 Jan 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Carbohydrates
Glycobiology
Glycoconjugates

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10.1016/j.carres.2014.10.005

Cite this

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title = "Recent progress in the field of glycoconjugates",

abstract = "The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and have provided new potential vaccines against cancer, viral, and bacterial infections and new biotechnological tools. This review aims to collect and compile the recent advances in the field of glycopeptides, glycoproteins, and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research, we hope that this review will inspire fruitful research in this important medicinal chemistry field.",

keywords = "Carbohydrates, Glycobiology, Glycoconjugates",

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T1 - Recent progress in the field of glycoconjugates

AU - Crucho, Carina I.C.

AU - Correia-Da-Silva, Paula

AU - Petrova, Krasimira T.

AU - Barros, M. Teresa

PY - 2015/1/30

Y1 - 2015/1/30

N2 - The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and have provided new potential vaccines against cancer, viral, and bacterial infections and new biotechnological tools. This review aims to collect and compile the recent advances in the field of glycopeptides, glycoproteins, and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research, we hope that this review will inspire fruitful research in this important medicinal chemistry field.

AB - The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and have provided new potential vaccines against cancer, viral, and bacterial infections and new biotechnological tools. This review aims to collect and compile the recent advances in the field of glycopeptides, glycoproteins, and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research, we hope that this review will inspire fruitful research in this important medicinal chemistry field.

KW - Carbohydrates

KW - Glycobiology

KW - Glycoconjugates

UR - https://www.scopus.com/pages/publications/84919625198

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DO - 10.1016/j.carres.2014.10.005

M3 - Review article

C2 - 25498012

AN - SCOPUS:84919625198

SN - 0008-6215

VL - 402

SP - 124

EP - 132

JO - Carbohydrate Research

JF - Carbohydrate Research

ER -

Recent progress in the field of glycoconjugates

Abstract

UN SDGs

Keywords

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