Risk, Burden of Bladder Cancer and THMs Exposure from Water Disinfection in Indoor Swimming Pools

Carla Costa; Ricardo Assunção; Diana Sequeira; Filipa Esteves; João Paulo Teixeira; Joana Madureira

Risk, Burden of Bladder Cancer and THMs Exposure from Water Disinfection in Indoor Swimming Pools

Carla Costa, Ricardo Assunção, Diana Sequeira, Filipa Esteves, João Paulo Teixeira, Joana Madureira

Research output: Contribution to conference › Paper › peer-review

Abstract

Trihalomethanes (THMs) have been associated via ingestion route with bladder cancer in the literature. This study aimed to estimate the lifetime cancer risk (LCR) and attributable burden of bladder cancer from exposure to THMs via ingestion in 238 study participants attending 10 Portuguese public indoor swimming pools. Swimming habits were collected via questionnaires and THMs levels were obtained from swimming pools water records. Two exposure scenarios were analysed using a probabilistic approach. Population-attributable fraction (PAF), number of attributable bladder cancer cases and disability adjusted life years (DALYs) were calculated based on Portuguese incidence rates, population size and DALYs rate reported in the Global Burden of Disease study. Results indicate that LCR associated to THMs exposure is higher than the negligible risk levels of 1×10^-6. The estimated PAF attributable to THMs exposure in Portugal is 0.07%, accounting for 2.4 bladder cancer cases per year; while DALYs were 198 per year.

Original language	English
Publication status	Published - 2022
Event	17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022 - Kuopio, Finland Duration: 12 Jun 2022 → 16 Jun 2022

Conference

Conference	17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022
Country/Territory	Finland
City	Kuopio
Period	12/06/22 → 16/06/22

Keywords

Human exposure
disinfection by-products
health risk assessment
ingestion
noncompetitive attendees

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@conference{e75ae111b59d4c32b1dd83706dfaf3ba,

title = "Risk, Burden of Bladder Cancer and THMs Exposure from Water Disinfection in Indoor Swimming Pools",

abstract = "Trihalomethanes (THMs) have been associated via ingestion route with bladder cancer in the literature. This study aimed to estimate the lifetime cancer risk (LCR) and attributable burden of bladder cancer from exposure to THMs via ingestion in 238 study participants attending 10 Portuguese public indoor swimming pools. Swimming habits were collected via questionnaires and THMs levels were obtained from swimming pools water records. Two exposure scenarios were analysed using a probabilistic approach. Population-attributable fraction (PAF), number of attributable bladder cancer cases and disability adjusted life years (DALYs) were calculated based on Portuguese incidence rates, population size and DALYs rate reported in the Global Burden of Disease study. Results indicate that LCR associated to THMs exposure is higher than the negligible risk levels of 1×10-6. The estimated PAF attributable to THMs exposure in Portugal is 0.07%, accounting for 2.4 bladder cancer cases per year; while DALYs were 198 per year.",

keywords = "Human exposure, disinfection by-products, health risk assessment, ingestion, noncompetitive attendees",

author = "Carla Costa and Ricardo Assun{\c c}{\~a}o and Diana Sequeira and Filipa Esteves and Teixeira, {Jo{\~a}o Paulo} and Joana Madureira",

note = "Publisher Copyright: {\textcopyright} 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.; 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022 ; Conference date: 12-06-2022 Through 16-06-2022",

year = "2022",

language = "English",

}

TY - CONF

T1 - Risk, Burden of Bladder Cancer and THMs Exposure from Water Disinfection in Indoor Swimming Pools

AU - Costa, Carla

AU - Assunção, Ricardo

AU - Sequeira, Diana

AU - Esteves, Filipa

AU - Teixeira, João Paulo

AU - Madureira, Joana

PY - 2022

Y1 - 2022

N2 - Trihalomethanes (THMs) have been associated via ingestion route with bladder cancer in the literature. This study aimed to estimate the lifetime cancer risk (LCR) and attributable burden of bladder cancer from exposure to THMs via ingestion in 238 study participants attending 10 Portuguese public indoor swimming pools. Swimming habits were collected via questionnaires and THMs levels were obtained from swimming pools water records. Two exposure scenarios were analysed using a probabilistic approach. Population-attributable fraction (PAF), number of attributable bladder cancer cases and disability adjusted life years (DALYs) were calculated based on Portuguese incidence rates, population size and DALYs rate reported in the Global Burden of Disease study. Results indicate that LCR associated to THMs exposure is higher than the negligible risk levels of 1×10-6. The estimated PAF attributable to THMs exposure in Portugal is 0.07%, accounting for 2.4 bladder cancer cases per year; while DALYs were 198 per year.

AB - Trihalomethanes (THMs) have been associated via ingestion route with bladder cancer in the literature. This study aimed to estimate the lifetime cancer risk (LCR) and attributable burden of bladder cancer from exposure to THMs via ingestion in 238 study participants attending 10 Portuguese public indoor swimming pools. Swimming habits were collected via questionnaires and THMs levels were obtained from swimming pools water records. Two exposure scenarios were analysed using a probabilistic approach. Population-attributable fraction (PAF), number of attributable bladder cancer cases and disability adjusted life years (DALYs) were calculated based on Portuguese incidence rates, population size and DALYs rate reported in the Global Burden of Disease study. Results indicate that LCR associated to THMs exposure is higher than the negligible risk levels of 1×10-6. The estimated PAF attributable to THMs exposure in Portugal is 0.07%, accounting for 2.4 bladder cancer cases per year; while DALYs were 198 per year.

KW - Human exposure

KW - disinfection by-products

KW - health risk assessment

KW - ingestion

KW - noncompetitive attendees

UR - http://www.scopus.com/inward/record.url?scp=85159215118&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:85159215118

T2 - 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022

Y2 - 12 June 2022 through 16 June 2022

ER -

Risk, Burden of Bladder Cancer and THMs Exposure from Water Disinfection in Indoor Swimming Pools

Abstract

Conference

Keywords

UN SDGs

Other files and links

Fingerprint

Cite this