Ultrastructure of the effects of pyrrolidine-fused chlorins on the replication of HSV-1

António P.A. Matos, Ana R.N. Santos, Maria F. Caeiro, Maria A.F. Faustino, M. G.P.M.S. Neves, A. C. Tomé, José A.S. Cavaleiro

Research output: Contribution to journalArticlepeer-review

Abstract

Currently, only few antiviral drugs of proven effectiveness exist against virus of the Herpesviridae family and viral resistance to these drugs, especially in the immunocompromised hosts, has encouraged research for new drugs. Some porphyrin derivatives revealed a significant antiviral activity against HSV-1 virus. However the cellular target of the porphyrin derivatives in the virus-cell complex remains unknown.

Original languageEnglish
Pages (from-to)137-138
Number of pages2
JournalMicroscopy and Microanalysis
Volume14
Issue numberSUPPL. 3
DOIs
Publication statusPublished - Sept 2008
Externally publishedYes

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