TY - JOUR
T1 - Vitamin D in dysphagic patients who have undergone endoscopic gastrostomy for long-term enteral feeding
AU - Santos, Carla Adriana
AU - Nunes, Gonçalo
AU - Barata, Ana Teresa
AU - Fonseca, Jorge
N1 - Publisher Copyright:
© 2020 Elsevier España, S.L.U.
PY - 2021/1
Y1 - 2021/1
N2 - Objective: Vitamin D plays a major role in biological processes. Its deficiency is associated with increased morbidity and mortality. Patients who have undergone endoscopic gastrostomy (PEG) present with protein-energy malnutrition, and may be at risk for Vitamin D deficiency, due to their age, less sunlight exposure and lower dietary intake. We aimed to determine the prevalence of hypovitaminosis D in PEG-patients, its change under PEG-feeding, and its relationship with serum proteins and risk factors for Vitamin D deficiency. Methods: This was a prospective observational study, over 4 weeks, after gastrostomy. Data were collected at the initial PEG procedure (T0), and after 4 weeks (T1). Initial evaluation included age, gender, underlying disorder, NRS-2002, BMI, serum albumin, transferrin and Vitamin D. At T1 we assessed Vit. D, albumin, and transferrin. Vitamin D was performed with Electrochemiluminescence through Elecsys 2010 assay. Patients were fed with blended homemade meals. Results: 200 patients (118 males), 22–92 years of age, were studied. There were initial low values for Vit. D (181), albumin (96), transferrin (121), and BMI (124). A correlation was found between Vit. D and serum albumin (r = 0.49, p = 0.005) but not with transferrin (r = 0.26, p = 0.195). At T1 the subgroup who had Vit. D levels assessed (n = 48) was part of the initial study group maintained low levels of Vitamin D despite nutritional intervention. Conclusion: We recommend systematic Vitamin D supplementation of PEG fed patients using homemade meals or at least screening for hypovitaminosis D as a routine part of their care.
AB - Objective: Vitamin D plays a major role in biological processes. Its deficiency is associated with increased morbidity and mortality. Patients who have undergone endoscopic gastrostomy (PEG) present with protein-energy malnutrition, and may be at risk for Vitamin D deficiency, due to their age, less sunlight exposure and lower dietary intake. We aimed to determine the prevalence of hypovitaminosis D in PEG-patients, its change under PEG-feeding, and its relationship with serum proteins and risk factors for Vitamin D deficiency. Methods: This was a prospective observational study, over 4 weeks, after gastrostomy. Data were collected at the initial PEG procedure (T0), and after 4 weeks (T1). Initial evaluation included age, gender, underlying disorder, NRS-2002, BMI, serum albumin, transferrin and Vitamin D. At T1 we assessed Vit. D, albumin, and transferrin. Vitamin D was performed with Electrochemiluminescence through Elecsys 2010 assay. Patients were fed with blended homemade meals. Results: 200 patients (118 males), 22–92 years of age, were studied. There were initial low values for Vit. D (181), albumin (96), transferrin (121), and BMI (124). A correlation was found between Vit. D and serum albumin (r = 0.49, p = 0.005) but not with transferrin (r = 0.26, p = 0.195). At T1 the subgroup who had Vit. D levels assessed (n = 48) was part of the initial study group maintained low levels of Vitamin D despite nutritional intervention. Conclusion: We recommend systematic Vitamin D supplementation of PEG fed patients using homemade meals or at least screening for hypovitaminosis D as a routine part of their care.
KW - Dysphagia
KW - Gastrostomy
KW - Nutrition
KW - PEG
KW - Vitamin D
UR - http://www.scopus.com/inward/record.url?scp=85094556687&partnerID=8YFLogxK
U2 - 10.1016/j.gastrohep.2020.05.016
DO - 10.1016/j.gastrohep.2020.05.016
M3 - Article
C2 - 33268156
AN - SCOPUS:85094556687
SN - 0210-5705
VL - 44
SP - 13
EP - 19
JO - Gastroenterologia y Hepatologia
JF - Gastroenterologia y Hepatologia
IS - 1
ER -