Detalhes do projeto
Description
1. To evaluate symptoms of gastrointestinal dysfunction in people with PWP;
2. To identify and describe PWP oral health status;
3. To study the PwP nasal, oral and fecal microbiota;
4. To confirm the presence of, and to characterize, alpha-synuclein aggregates in gut biopsy specimens of PWP;
5. To study the PwP microbiome in gut biopsy;
6. In PwP, to correlate the burden of gastrointestinal dysfunction, oral health problems, microbiota dysbiosis and gut alpha-synuclein aggregates with disease duration, severity, motor and non-motor features, ongoing treatment, depression and QoL.
2. To identify and describe PWP oral health status;
3. To study the PwP nasal, oral and fecal microbiota;
4. To confirm the presence of, and to characterize, alpha-synuclein aggregates in gut biopsy specimens of PWP;
5. To study the PwP microbiome in gut biopsy;
6. In PwP, to correlate the burden of gastrointestinal dysfunction, oral health problems, microbiota dysbiosis and gut alpha-synuclein aggregates with disease duration, severity, motor and non-motor features, ongoing treatment, depression and QoL.
| Acrónimo | GutSPark |
|---|---|
| Estado | Terminado |
| Data de início/fim efetiva | 31/01/22 → 31/01/24 |
Objetivos de Desenvolvimento Sustentável da ONU
Em 2015, os estados membros da ONU acordaram 17 Objetivos de Desenvolvimento Sustentável (ODS) globais para acabar com a pobreza, proteger o planeta e garantir a prosperidade para todos. O projeto contribui para o(s) seguinte(s) ODS:
Impressão digital
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