Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study

Francisca Bartilotti Matos; Dara Mbanze; Perpétua Gomes; Cristóvão Figueiredo; Daniel Coutinho; Sofia Nunes; Carlos Azevedo; Joana Fragoso; Tiago Teixeira; Luís Malheiro

doi:10.1177/09564624241296583

Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study

Francisca Bartilotti Matos
, Dara Mbanze
, Perpétua Gomes
, Cristóvão Figueiredo
, Daniel Coutinho
, Sofia Nunes
, Carlos Azevedo
, Joana Fragoso
, Tiago Teixeira
, Luís Malheiro

Resultado de pesquisa: ???type-name??? › ???researchoutput.researchoutputtypes.contributiontojournal.article??? › revisão de pares

2 Citações (Scopus)

Resumo

Resistance to antiretroviral therapy is an increasing challenge in the management of HIV. We present the case of a woman living with HIV, with a history of multiple treatment regimens and resistances to antiretrovirals, who has been successfully treated with a combination of lenacapavir and fostemsavir for the past year, obtaining an undetectable viral load within one month of starting therapy and reporting no serious side effects. This case is amongst the first to document the combined use of lenacapivir and fostemsavir in treating multidrug-resistant HIV. It supports the potential of these novel agents in managing complex cases of HIV resistance.

Idioma original	???core.languages.en_GB???
Páginas (de-até)	161-163
Número de páginas	3
Revista	International Journal of STD and AIDS
Volume	36
Número de emissão	2
DOIs	https://doi.org/10.1177/09564624241296583
Estado da publicação	???researchoutput.status.published??? - 1 nov. 2024

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title = "Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study",

abstract = "Resistance to antiretroviral therapy is an increasing challenge in the management of HIV. We present the case of a woman living with HIV, with a history of multiple treatment regimens and resistances to antiretrovirals, who has been successfully treated with a combination of lenacapavir and fostemsavir for the past year, obtaining an undetectable viral load within one month of starting therapy and reporting no serious side effects. This case is amongst the first to document the combined use of lenacapivir and fostemsavir in treating multidrug-resistant HIV. It supports the potential of these novel agents in managing complex cases of HIV resistance.",

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author = "Matos, \{Francisca Bartilotti\} and Dara Mbanze and Perp{\'e}tua Gomes and Crist{\'o}v{\~a}o Figueiredo and Daniel Coutinho and Sofia Nunes and Carlos Azevedo and Joana Fragoso and Tiago Teixeira and Lu{\'i}s Malheiro",

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doi = "10.1177/09564624241296583",

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Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study. / Matos, Francisca Bartilotti; Mbanze, Dara; Gomes, Perpétua et al.
Em: International Journal of STD and AIDS, Vol. 36, N.º 2, 01.11.2024, p. 161-163.

Resultado de pesquisa: ???type-name??? › ???researchoutput.researchoutputtypes.contributiontojournal.article??? › revisão de pares

TY - JOUR

T1 - Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir

T2 - A case study

AU - Matos, Francisca Bartilotti

AU - Mbanze, Dara

AU - Gomes, Perpétua

AU - Figueiredo, Cristóvão

AU - Coutinho, Daniel

AU - Nunes, Sofia

AU - Azevedo, Carlos

AU - Fragoso, Joana

AU - Teixeira, Tiago

AU - Malheiro, Luís

PY - 2024/11/1

Y1 - 2024/11/1

N2 - Resistance to antiretroviral therapy is an increasing challenge in the management of HIV. We present the case of a woman living with HIV, with a history of multiple treatment regimens and resistances to antiretrovirals, who has been successfully treated with a combination of lenacapavir and fostemsavir for the past year, obtaining an undetectable viral load within one month of starting therapy and reporting no serious side effects. This case is amongst the first to document the combined use of lenacapivir and fostemsavir in treating multidrug-resistant HIV. It supports the potential of these novel agents in managing complex cases of HIV resistance.

AB - Resistance to antiretroviral therapy is an increasing challenge in the management of HIV. We present the case of a woman living with HIV, with a history of multiple treatment regimens and resistances to antiretrovirals, who has been successfully treated with a combination of lenacapavir and fostemsavir for the past year, obtaining an undetectable viral load within one month of starting therapy and reporting no serious side effects. This case is amongst the first to document the combined use of lenacapivir and fostemsavir in treating multidrug-resistant HIV. It supports the potential of these novel agents in managing complex cases of HIV resistance.

KW - antiviral

KW - ART (antiretroviral therapy)

KW - HIV (Human immunodeficiency virus)

KW - other

KW - treatment

KW - viral disease

UR - https://www.scopus.com/pages/publications/85208202290

U2 - 10.1177/09564624241296583

DO - 10.1177/09564624241296583

M3 - Article

AN - SCOPUS:85208202290

SN - 0956-4624

VL - 36

SP - 161

EP - 163

JO - International Journal of STD and AIDS

JF - International Journal of STD and AIDS

IS - 2

ER -

Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study

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