HIV-1 genetic variants circulation in the North of Angola

A. Abecasis; D. Paraskevis; M. Epalanga; M. Fonseca; F. Burity; J. Bartolomeu; A. P. Carvalho; P. Gomes; A. M. Vandamme; R. Camacho

doi:10.1016/j.meegid.2004.07.007

HIV-1 genetic variants circulation in the North of Angola

A. Abecasis
, D. Paraskevis
, M. Epalanga
, M. Fonseca
, F. Burity
, J. Bartolomeu
, A. P. Carvalho
, P. Gomes
, A. M. Vandamme
, R. Camacho

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22 Citações (Scopus)

Resumo

Few molecular epidemiological data on HIV-1 in Angola are available. In this study, we analysed 37 pol sequences from patients originated from Luanda and Cabinda in Angola. It was our objective to investigate the circulation of different HIV-1 subtypes in this country. We found a high HIV-1 genetic diversity. The predominant subtypes were C and F, while subtypes A, D, G and H were also detected. Three sequences were untypable and may possibly belong to new subtypes or recombinants of unknown subtypes. Moreover, 13 recombinant sequences were found, most of them with very complex patterns including untypable fragments.

Idioma original	???core.languages.en_GB???
Páginas (de-até)	231-237
Número de páginas	7
Revista	Infection, Genetics and Evolution
Volume	5
Número de emissão	3 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.meegid.2004.07.007
Estado da publicação	???researchoutput.status.published??? - abr. 2005
Publicado externamente	Sim

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10.1016/j.meegid.2004.07.007

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@article{4643e3784cca4434b70d5d9fe98664ef,

title = "HIV-1 genetic variants circulation in the North of Angola",

abstract = "Few molecular epidemiological data on HIV-1 in Angola are available. In this study, we analysed 37 pol sequences from patients originated from Luanda and Cabinda in Angola. It was our objective to investigate the circulation of different HIV-1 subtypes in this country. We found a high HIV-1 genetic diversity. The predominant subtypes were C and F, while subtypes A, D, G and H were also detected. Three sequences were untypable and may possibly belong to new subtypes or recombinants of unknown subtypes. Moreover, 13 recombinant sequences were found, most of them with very complex patterns including untypable fragments.",

keywords = "HIV-1 genetic variants, HIV-1 subtypes, Recombinant sequences",

author = "A. Abecasis and D. Paraskevis and M. Epalanga and M. Fonseca and F. Burity and J. Bartolomeu and Carvalho, \{A. P.\} and P. Gomes and Vandamme, \{A. M.\} and R. Camacho",

note = "Funding Information: A.A. was supported by a Associa{\c c}{\~a}o Portuguesa para o Estudo Cl{\'i}nico da SIDA (APECS) and Gilead Sciences Lda. fellowship. D.P. was supported by a Marie Curie fellowship from the European Commission (QLK2-CT2001-51062). This work was partly supported by the Flemish Fonds voor Wetenschappelijk Onderzoek (FWO G.0288.01). ",

year = "2005",

month = apr,

doi = "10.1016/j.meegid.2004.07.007",

language = "English",

volume = "5",

pages = "231--237",

journal = "Infection, Genetics and Evolution",

issn = "1567-1348",

publisher = "Elsevier B.V.",

number = "3 SPEC. ISS.",

}

TY - JOUR

T1 - HIV-1 genetic variants circulation in the North of Angola

AU - Abecasis, A.

AU - Paraskevis, D.

AU - Epalanga, M.

AU - Fonseca, M.

AU - Burity, F.

AU - Bartolomeu, J.

AU - Carvalho, A. P.

AU - Gomes, P.

AU - Vandamme, A. M.

AU - Camacho, R.

N1 - Funding Information: A.A. was supported by a Associação Portuguesa para o Estudo Clínico da SIDA (APECS) and Gilead Sciences Lda. fellowship. D.P. was supported by a Marie Curie fellowship from the European Commission (QLK2-CT2001-51062). This work was partly supported by the Flemish Fonds voor Wetenschappelijk Onderzoek (FWO G.0288.01).

PY - 2005/4

Y1 - 2005/4

N2 - Few molecular epidemiological data on HIV-1 in Angola are available. In this study, we analysed 37 pol sequences from patients originated from Luanda and Cabinda in Angola. It was our objective to investigate the circulation of different HIV-1 subtypes in this country. We found a high HIV-1 genetic diversity. The predominant subtypes were C and F, while subtypes A, D, G and H were also detected. Three sequences were untypable and may possibly belong to new subtypes or recombinants of unknown subtypes. Moreover, 13 recombinant sequences were found, most of them with very complex patterns including untypable fragments.

AB - Few molecular epidemiological data on HIV-1 in Angola are available. In this study, we analysed 37 pol sequences from patients originated from Luanda and Cabinda in Angola. It was our objective to investigate the circulation of different HIV-1 subtypes in this country. We found a high HIV-1 genetic diversity. The predominant subtypes were C and F, while subtypes A, D, G and H were also detected. Three sequences were untypable and may possibly belong to new subtypes or recombinants of unknown subtypes. Moreover, 13 recombinant sequences were found, most of them with very complex patterns including untypable fragments.

KW - HIV-1 genetic variants

KW - HIV-1 subtypes

KW - Recombinant sequences

UR - https://www.scopus.com/pages/publications/20044396370

U2 - 10.1016/j.meegid.2004.07.007

DO - 10.1016/j.meegid.2004.07.007

M3 - Article

C2 - 15737914

AN - SCOPUS:20044396370

SN - 1567-1348

VL - 5

SP - 231

EP - 237

JO - Infection, Genetics and Evolution

JF - Infection, Genetics and Evolution

IS - 3 SPEC. ISS.

ER -

HIV-1 genetic variants circulation in the North of Angola

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