Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient

The cosmetic industry is continually searching for innovative ingredients, and there is a current trend in sourcing materials of natural origin. The Hermetia illucens (Linnaeus) larvae biomass is a potential source of compounds with applicability in cosmetics due to its high lipid, protein, and polysaccharide content. High concentrations of lauric acid, also known for also having antimicrobial properties, may be obtained from the lipid fraction. Additionally, these larvae are known to have a well-developed immune system, surviving in decomposition habitats, and can be induced to produce antimicrobial peptides (AMP's). These substances could be probed as alternative preservatives in cosmetics, as consumers are often concerned with the safety of conventional preservatives, such as parabens. The present study conducted a preliminary assessment of the antimicrobial activity of the crude extracts obtained from different extraction methods and extraction solvents against four microorganisms (Gram-positive and negative bacteria and yeasts). The use of diluted extracts did not show relevant inhibition of the growth of the tested microorganisms compared to the positive controls. Further assays are foreseen to test the antimicrobial activity of compounds or fractions isolated from the crude extracts.