TY - GEN
T1 - Production of biopolyhydroxyalkanoates
AU - De Almeida, Catarina Dias
AU - Cesario, Maria Teresa
AU - Da Fonseca, Manuela Regalo
PY - 2011
Y1 - 2011
N2 - This work focuses on developing high productivity and economically viable processes for the production of biopolyesters with potential uses in biomedical fields. High cell density fed-batch cultures of Cupriavidus necator on waste glycerol were used to produce the copolymer P(3HB-co-4HB). The incorporation of 4HB monomers within the polymeric chain was achieved through the concomitant feeding of gamma-butyrolactone (GBL). Acetic and propionic acid were tested as stimulators to enhance 4HB incorporation. When propionic acid was used, a terpolymer P(3HB-co-4HB-co-3HV) was originated. P(3HB-co-4HB) copolymers with molar % of 4HB from 1.8 % to 12.3 % were produced with productivities between 0.09 gP(3HB-4HB). L1.h1 and 0.79 g P(3HB-4HB) L1.h1.
AB - This work focuses on developing high productivity and economically viable processes for the production of biopolyesters with potential uses in biomedical fields. High cell density fed-batch cultures of Cupriavidus necator on waste glycerol were used to produce the copolymer P(3HB-co-4HB). The incorporation of 4HB monomers within the polymeric chain was achieved through the concomitant feeding of gamma-butyrolactone (GBL). Acetic and propionic acid were tested as stimulators to enhance 4HB incorporation. When propionic acid was used, a terpolymer P(3HB-co-4HB-co-3HV) was originated. P(3HB-co-4HB) copolymers with molar % of 4HB from 1.8 % to 12.3 % were produced with productivities between 0.09 gP(3HB-4HB). L1.h1 and 0.79 g P(3HB-4HB) L1.h1.
KW - Cupriavidus necator DSM 545
KW - P(3HB-co-4HB)
KW - PHA
KW - biopolyesters
KW - waste glycerol
UR - http://www.scopus.com/inward/record.url?scp=80053980609&partnerID=8YFLogxK
U2 - 10.1109/ENBENG.2011.6026078
DO - 10.1109/ENBENG.2011.6026078
M3 - Conference contribution
AN - SCOPUS:80053980609
SN - 9781457705229
T3 - 1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011
BT - 1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011
T2 - 2011 1st Portuguese Meeting in Bioengineering: The Challenge of the XXI Century, ENBENG 2011
Y2 - 1 March 2011 through 4 March 2011
ER -