Rapid clinical progression to AIDS and death in a persistently seronegative HIV-1 infected heterosexual young man

Inês Bártolo; Ricardo Camacho; Helena Barroso; Victor Bezerra; Nuno Taveira

doi:10.1097/QAD.0b013e328332d5e1

Rapid clinical progression to AIDS and death in a persistently seronegative HIV-1 infected heterosexual young man

Inês Bártolo
, Ricardo Camacho
, Helena Barroso
, Victor Bezerra
, Nuno Taveira

Resultado de pesquisa: ???type-name??? › ???researchoutput.researchoutputtypes.contributiontojournal.article??? › revisão de pares

10 Citações (Scopus)

Resumo

Seronegative HIV-1 infection has important implications for diagnosis and prevention. We describe a case of HIV-1 infection without seroconversion and fast progression to AIDS and death. Genetic and phylogenetic analysis indicated that the patient was infected with a CRF14-BG-like strain selectively transmitted by his seropositive sexual partner. The results suggest a massive infection with a highly aggressive CRF14-BG-like strain and/or the presence of an unidentified immunological deficiency that has prevented the formation of HIV-1-specific antibodies.

Idioma original	???core.languages.en_GB???
Páginas (de-até)	2359-2362
Número de páginas	4
Revista	AIDS
Volume	23
Número de emissão	17
DOIs	https://doi.org/10.1097/QAD.0b013e328332d5e1
Estado da publicação	???researchoutput.status.published??? - nov. 2009

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Este resultado contribui para o(s) seguinte(s) Objetivo(s) de Desenvolvimento Sustentável

ODS 3 Boa saúde e bem-estar
ODS 5 Igualdade de género

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10.1097/QAD.0b013e328332d5e1

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abstract = "Seronegative HIV-1 infection has important implications for diagnosis and prevention. We describe a case of HIV-1 infection without seroconversion and fast progression to AIDS and death. Genetic and phylogenetic analysis indicated that the patient was infected with a CRF14-BG-like strain selectively transmitted by his seropositive sexual partner. The results suggest a massive infection with a highly aggressive CRF14-BG-like strain and/or the presence of an unidentified immunological deficiency that has prevented the formation of HIV-1-specific antibodies.",

author = "In{\^e}s B{\'a}rtolo and Ricardo Camacho and Helena Barroso and Victor Bezerra and Nuno Taveira",

year = "2009",

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T1 - Rapid clinical progression to AIDS and death in a persistently seronegative HIV-1 infected heterosexual young man

AU - Bártolo, Inês

AU - Camacho, Ricardo

AU - Barroso, Helena

AU - Bezerra, Victor

AU - Taveira, Nuno

PY - 2009/11

Y1 - 2009/11

N2 - Seronegative HIV-1 infection has important implications for diagnosis and prevention. We describe a case of HIV-1 infection without seroconversion and fast progression to AIDS and death. Genetic and phylogenetic analysis indicated that the patient was infected with a CRF14-BG-like strain selectively transmitted by his seropositive sexual partner. The results suggest a massive infection with a highly aggressive CRF14-BG-like strain and/or the presence of an unidentified immunological deficiency that has prevented the formation of HIV-1-specific antibodies.

AB - Seronegative HIV-1 infection has important implications for diagnosis and prevention. We describe a case of HIV-1 infection without seroconversion and fast progression to AIDS and death. Genetic and phylogenetic analysis indicated that the patient was infected with a CRF14-BG-like strain selectively transmitted by his seropositive sexual partner. The results suggest a massive infection with a highly aggressive CRF14-BG-like strain and/or the presence of an unidentified immunological deficiency that has prevented the formation of HIV-1-specific antibodies.

UR - https://www.scopus.com/pages/publications/70449344717

U2 - 10.1097/QAD.0b013e328332d5e1

DO - 10.1097/QAD.0b013e328332d5e1

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ER -

Rapid clinical progression to AIDS and death in a persistently seronegative HIV-1 infected heterosexual young man

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