Resumo
Trihalomethanes (THMs) have been associated via ingestion route with bladder cancer in the literature. This study aimed to estimate the lifetime cancer risk (LCR) and attributable burden of bladder cancer from exposure to THMs via ingestion in 238 study participants attending 10 Portuguese public indoor swimming pools. Swimming habits were collected via questionnaires and THMs levels were obtained from swimming pools water records. Two exposure scenarios were analysed using a probabilistic approach. Population-attributable fraction (PAF), number of attributable bladder cancer cases and disability adjusted life years (DALYs) were calculated based on Portuguese incidence rates, population size and DALYs rate reported in the Global Burden of Disease study. Results indicate that LCR associated to THMs exposure is higher than the negligible risk levels of 1×10-6. The estimated PAF attributable to THMs exposure in Portugal is 0.07%, accounting for 2.4 bladder cancer cases per year; while DALYs were 198 per year.
Idioma original | ???core.languages.en_GB??? |
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Estado da publicação | ???researchoutput.status.published??? - 2022 |
Evento | 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022 - Kuopio Duração: 12 jun. 2022 → 16 jun. 2022 |
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???event.eventtypes.event.conference??? | 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022 |
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País/Território | Finland |
Cidade | Kuopio |
Período | 12/06/22 → 16/06/22 |