TY - GEN
T1 - Sedentary behaviour, physical activity, physical fitness and subclinical atherosclerosis in 11-12 years-old children
AU - Melo, Xavier
AU - Santa-Clara, Helena
AU - Martins, Sandra S.
AU - Minderico, Cláudia S.
AU - Fernhall, Bo
AU - Sardinha, Luís B.
PY - 2013
Y1 - 2013
N2 - Aim: Examine the influence of sedentary behaviour (SED), physical activity (PA), muscular strength (MS) and cardiorespiratory fitness (CRF) on subclinical atherosclerosis in 11-12 years-old children. Methods: We assessed intima-media thickness (IMT) of the common carotid artery in 366 children aged 11-12 years-old (191 girls). Measures included IMT assessed with high-resolution ultrasonography, pulse pressure (PP), a maximal handgrip strength test, body mass index, waist circumference, body fat mass and lean mass (LEAN) from DXA and CRF determined using a maximal cycle ergometer test. SED and PA were assessed by accelerometry. MS was adjusted for LEAN yielding relative MS (RMS). Association between IMT and RMS adjusted for SED, PA and CRF were tested with multiple linear regression analysis. Differences in risk factors among RMS groups were tested with ANOVA/ANCOVA. Results: RMS was related to IMT independently of PA, CRF, age, gender, maturity and PP (p<0.05). As compared with the higher RMS group, subjects in the lower RMS group had increased body composition phenotypes, hemodynamics and IMT, and lower moderate-vigorous PA, MS and CRF (p<0.05). Full modelling exposed the detrimental and independent role of RMS in arterial structure in 11-12 years-old children. Greater RMS is associated with improved vascular health even in children.
AB - Aim: Examine the influence of sedentary behaviour (SED), physical activity (PA), muscular strength (MS) and cardiorespiratory fitness (CRF) on subclinical atherosclerosis in 11-12 years-old children. Methods: We assessed intima-media thickness (IMT) of the common carotid artery in 366 children aged 11-12 years-old (191 girls). Measures included IMT assessed with high-resolution ultrasonography, pulse pressure (PP), a maximal handgrip strength test, body mass index, waist circumference, body fat mass and lean mass (LEAN) from DXA and CRF determined using a maximal cycle ergometer test. SED and PA were assessed by accelerometry. MS was adjusted for LEAN yielding relative MS (RMS). Association between IMT and RMS adjusted for SED, PA and CRF were tested with multiple linear regression analysis. Differences in risk factors among RMS groups were tested with ANOVA/ANCOVA. Results: RMS was related to IMT independently of PA, CRF, age, gender, maturity and PP (p<0.05). As compared with the higher RMS group, subjects in the lower RMS group had increased body composition phenotypes, hemodynamics and IMT, and lower moderate-vigorous PA, MS and CRF (p<0.05). Full modelling exposed the detrimental and independent role of RMS in arterial structure in 11-12 years-old children. Greater RMS is associated with improved vascular health even in children.
KW - Atherosclerosis
KW - Cardiorespiratory Fitness
KW - Children
KW - Common Carotid Artery
KW - Intima-media Thickness
KW - Muscular Strength
KW - Physical Activity
KW - Sedentary Behaviour
UR - https://www.scopus.com/pages/publications/84887259131
M3 - Conference contribution
AN - SCOPUS:84887259131
SN - 9789898565785
T3 - CARDIOTECHNIX 2013 - Proceedings of the International Congress on Cardiovascular Technologies
SP - 22
EP - 26
BT - CARDIOTECHNIX 2013 - Proceedings of the International Congress on Cardiovascular Technologies
T2 - 1st International Congress on Cardiovascular Technologies, CARDIOTECHNIX 2013
Y2 - 19 September 2013 through 21 September 2013
ER -