Resumo
The present study intended to study the influence of Phaseolus vulgaris beans in mammary carcinogenesis especially considering the main malignancy indicators through a histopathology study. A total of 72 female rats 50 days old were divided in three groups and hold in constant conditions temperature, light and humidity. Group B and C received 20 mg of 7, 12 dimethyl benzanthracene by gavages. All the animals were fed with the same standard food, group C were supplemented with Phaseolus vulgaris beans. The study had last for 150 days. Tumors in group C animals had lower pattern grades and lower mitotic counts despite the higher weight gain in this group. These results suggest a protective role of bean consumption in mammary carcinogenesis possibly due to fiber and oligossacharides content, especially present in Phaseolus vulgaris from "padrão tarrestre" species.
Idioma original | ???core.languages.en_GB??? |
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Páginas (de-até) | 125-134 |
Número de páginas | 10 |
Revista | International Journal of Cancer Research |
Volume | 7 |
Número de emissão | 2 |
DOIs | |
Estado da publicação | ???researchoutput.status.published??? - 2011 |