Ultrastructure of the effects of pyrrolidine-fused chlorins on the replication of HSV-1

  • António P.A. Matos
  • , Ana R.N. Santos
  • , Maria F. Caeiro
  • , Maria A.F. Faustino
  • , M. G.P.M.S. Neves
  • , A. C. Tomé
  • , José A.S. Cavaleiro

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Resumo

Currently, only few antiviral drugs of proven effectiveness exist against virus of the Herpesviridae family and viral resistance to these drugs, especially in the immunocompromised hosts, has encouraged research for new drugs. Some porphyrin derivatives revealed a significant antiviral activity against HSV-1 virus. However the cellular target of the porphyrin derivatives in the virus-cell complex remains unknown.

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Páginas (de-até)137-138
Número de páginas2
RevistaMicroscopy and Microanalysis
Volume14
Número de emissãoSUPPL. 3
DOIs
Estado da publicação???researchoutput.status.published??? - set. 2008
Publicado externamenteSim

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